Use of Pharmacokinetic Data Below Lower Limit of Quantitation Values
نویسندگان
چکیده
منابع مشابه
Incorporation of concentration data below the limit of quantification in population pharmacokinetic analyses
Handling of data below the lower limit of quantification (LLOQ), below the limit of quantification (BLOQ) in population pharmacokinetic (PopPK) analyses is important for reducing bias and imprecision in parameter estimation. We aimed to evaluate whether using the concentration data below the LLOQ has superior performance over several established methods. The performance of this approach ("All d...
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ژورنال
عنوان ژورنال: Pharmaceutical Research
سال: 2012
ISSN: 0724-8741,1573-904X
DOI: 10.1007/s11095-012-0805-6